Cardiology Letters 2022, 31(5):298-32

Primary hyperaldosteronism - an often underestimated reason for arterial hypertension

Lazúrová I

1. interná klinika UPJŠ LF a UNLP Košice, Slovenská republika

Primary hyperaldosteronism (PH), i.e. Conn syndrome, is considered the most common cause of endocrine hypertension with the prevalence of 5-10% in the general population of hypertensive subjects and 20-30% in patients with resistant and severe hypertension. Therefore its systematic screening among hypertonics is very important. Screening of PH should be a part of differential diagnosis in selected groups of hypertonics, especially those with resistant or severe diastolic hypertension. Because long term aldosterone overproduction may cause severe organ complications such as cardiovascular and cerebrovascular events and renal impairment, it is necessary to recognize and to treat this syndrome very early. This review is focused on clinical management of patients with PH based on current guidelines.

Keywords: primary hyperaldosteronism; aldosterone-renin ratio; screening; diagnosis; treatment

Published: May 1, 2022  Show citation