Cardiology Letters 2018, 27(2):106-109
Early graft thrombosis following CABG due to antithrombin-III deficiency
- Clinic of Cardiac surgery, The National Institute of Cardiovascular Diseases, Bratislava, Slovak Republic
Early graft failure after coronary bypass grafting is a serious complication which may result in acute myocardial ischemia. In this report we present the case of a 79-year-old female patient with repeated multiple graft thrombosis of initially unclear origin which, after further investigation, was most likely caused by acquired antithrombin III deficiency. Although antithrombin III deficiency is a rare complication, in the case of simultaneous acute grafts thrombosis after cardiac revascularization surgery, it should be considered as a probable cause.
Keywords: multiple early graft thrombosis; coronary artery bypass grafting; acquired AT III deficiency
Published: February 1, 2018 Show citation
References
- Thielmann M, Massoudy P, Jaeger BR, et al. Emergency rerevascularization with percutaneous coronary intervention, reoperation, or conservative treatment in patients with acute perioperative graft failure following coronary artery bypass surgery. Eur J Cardiothorac Surg 2006:30(1):117-125.
Go to original source... - Thielmann M, Massoudy P, Schmermund A, et al. Diagnostic discrimination between graft-related and non-graft-related perioperative myocardial infarction with cardiac troponin I after coronary artery bypass surgery. Eur Heart J. 2005:26(22):24402247.
Go to original source... - Holmvang L, Jurlander B, Rasmussen C, et al. Use of biochemical markers of infarction for diagnosing perioperative myocardial infarction and early graft occlusion after coronary artery bypass surgery. Chest. 2002:121(1):103-111.
Go to original source... - Laflamme M, DeMey N, Bouchard D, et al. Management of early postoperative coronary artery bypass graft failure. Interact Cardiovasc Thorac Surg. 2012:14(4):452-456.
Go to original source... - Gaman AM, Gaman GD. Deficiency of antithrombin III (AT III)-Case report and review of the literature. Curr Health Sci J 2014:40(2):141-143.
- Kovacevic P, Velicki L, Komazec N, et al. Early graft thrombosis due to antithrombin III deficiency following CABG. Herz. 2011:36(2):144-146.
Go to original source...

