Cardiology Letters 2013, 22(2):115-124
Current trends in management of STEMI in the Slovak Republic. The analysis of the SLOVAKS-2 registry from 2011.
- 1 Kardiocentrum FNsP J. A. Reimana v Prešove
- 2 I. interná klinika Univerzitnej nemocnice v Martine
- 3 Národný ústav srdcových a cievnych chorôb a.s. v Bratislave
- 4 Kardiocentrum Nitra, s.r.o. v Nitre
- 5 V. interná klinika Univerzitnej nemocnice v Bratislave, Slovenská republika
Objective: Analysis of the management of STEMI patients in the Slovakia in 2011. The aim of the analysis is bring attention to inadequacies, and to support implementation of the latest medical knowledge into the clinical practice.
Methods and results: Data collection was conducted in August and September 2011. We have evaluated data from 69 treatment sites in Slovakia. These sites represents 85% of all workplaces treating ACS patients in the country. In this analysis we have evaluated of 1580 cases of ACS (STEMI, UAP and NSTEMI). STEMI cases represent 30.6% of all ACS. The average age of patients with STEMI was 63.8 (± 12.8). Representation of women was 30%. 80.6% of STEMI patients were admitted to PCI-centres. This was as primary hospitalization or secondary transfer. The proportion of STEMI admitted via EMS reached 88.7%. Primary reperfusion treatment was accomplished in 76.0% of patients (64.7% primary PCI, 11.3% fibrinolysis). 82.3% STEMI patients were admitted within 12 hours of symptom onset. The median of total ischemic time was 219 minutes. Our analysis confirms a very good standard of pharmacological treatment (98.3% aspirin, 92.6% clopidogrel, 93.5% statins, 85.3% ACE/AT1, 87.6 beta-blockers). In-hospital and 6-month STEMI mortality was 5.99% and 13.79%. The most common cause of death was cardiogenic shock (69.0% of all deaths).
Conclusion: In the year 2011 we saw a positive trend in increasing the proportion of patients treated with primary PCI. Hospital mortality decreased and total ischemic time shortened significantly. A persistent problem is the remarkable time delay incurred by patients themselves and the inadequate ability of EMS personnel to perform ECG diagnostic of STEMI on site. Introducing of primary reperfusion treatment within aceptable time interval and optimalization of antithrombotic regimen remain the main challenges for medical personnel in the nearest future.
Keywords: acute coronary syndrome; STEMI; primary PCI; reperfusion treatment; transport; time intervals; mortality; registry; SLOVAKS
Published: February 1, 2013 Show citation
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References
- Studenčan M, Hricák V, Kovář F, Kurray P, Murín J, Kamenský G, et al. Význam cielených organizačných opatrení pre implementáciu oficiálnych odporúčaní pre manažment pacientov so STEMI do klinickej praxe. Analýza výsledkov registra SLOVAKS 2007 - 2008. Cardiology sk 2010;19(1):55-67.
- Kovář F, Studenčan M, Hricák V, Kurray P, Murín J, Kamenský G, et al. Manažment pacientov s akútnym koronárnym syndrómom bez elevácií segmentov ST. Analýza výsledkov registra SLOVAKS z roku 2008. Cardiology sk 2010;19(3):181-191.
- Studenčan M. SLOvenský register Akútnych Koronárnych Syndrómov - SLOVAKS. Ďalšie smerovanie. Cardiology Lett. 2011;20(3):204-206.
- Widimsky P, Zelizko M, Jansky P, Tousek F, Holm F, Aschermann M. The incidence, treatment strategies and outcomes of acute coronary syndromes in the "reperfusion network" of different hospital types in the Czech Republic: results of the Czech evaluation of acute coronary syndromes in hospitalized patients (CZECH) registry. Int. J. Cardiol. 2007;119(2):212219.
Go to original source... - Widimsky P, Wijns W, Fajadet J, de Belder M, Knot J, Aaberge L, et al. Reperfusion therapy for ST elevation acute myocardial infarction in Europe: description of the current situation in 30 countries. Eur Heart J 2010;31(8):943-957.
Go to original source... - Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Lancet 1988;2(8607):349-360.
- Cagáň S, Moťovská Z, Besedová I, Jurkovičová O, Wimmerová S. Manažment akútneho infarktu myokardu. Kompendium medicíny. Mimoriadna príloha zdravotníckych novín 2004:331.
- Lowel H, Meisinger C, Heier M, Hormann A. The populationbased acute myocardial infarction (AMI) registry of the MONICA/KORA study region of Augsburg. Gesundheitswesen 2005;67(Suppl 1):S31-37.
Go to original source... - Selker HP, Raitt MH, Schmid CH, Laks MM, Beshansky JR, Griffith JL, et al. Time-dependent predictors of primary cardiac arrest in patients with acute myocardial infarction. Am Journal Cardiol 2003;91(3):280-286.
Go to original source... - White HD, Chew DP. Acute myocardial infarction. Lancet 2008;372(9638):570-584.
Go to original source... - Steg PG, James SK, Atar D, Badano LP, Lundqvist CB, Borger MA, et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC). Eur Heart J 2012;33(20):2569-2619.
Go to original source... - Montalescot G, Wiviott SD, Braunwald E, Murphy SA, Gibson CM, McCabe CH, et al. Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITONTIMI 38): double-blind, randomised controlled trial. Lancet 2009;373(9665):723-731.
Go to original source... - Wallentin L, Becker RC, Budaj A, Cannon CP, Emanuelsson H, Held C, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Eng J Med 2009;361(11):1045-1057.
Go to original source... - Steg PG, James S, Harrington RA, Ardissino D, Becker RC, Cannon CP, et al. Ticagrelor versus clopidogrel in patients with STelevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis. Circulation 2010;122(21):2131-2141.
Go to original source... - Silvain J, Montalescot G. Anticoagulant for primary percutaneous coronary intervention - the last dance for unfractionated heparin? Archives of cardiovascular diseases 2012;105(5):259-261.
Go to original source... - Studenčan M, Hricák V, Kovář F, Dobiáš V, Kurray P, Fridrich V, Čenčarik J, Mečiar P. Včasný manažment akútneho infarktu myokardu s eleváciami ST na EKG (STEMI). Odporúčania Slovenskej kardiologickej spoločnosti a Spoločnosti urgentnej medicíny a medicíny katastrof. Cardiology Lett. 2013;22(1):8593.
- Waksman R. Outcome improvement for STEMI patients: The next breakthrough in Interventional Cardiology. Cardiovasc Rev Med 2013:14 (1):1-2.
Go to original source...

