Cardiology Letters, 2022 (vol. 31), issue 4
Original article
Comparison of right ventricular function in patients undergoing transcatheter aortic valve implantation and surgical aortic valve replacement
Poliacikova P, Hrinova M, Hudec M, Belicova M
Cardiology Letters 2022, 31(4):213-220 
Aim: Comparison of the impact of surgical and transcatheter aortic valve replacement on the right ventricular function in patients with severe aortic stenosis. Methods and results: We performed a prospective analysis of right ventricular function parameters (TAPSE, RVPSV and FAC) of 50 TAVI and 50 AVR patients at three time intervals - preoperatively, up to 7 days and after 6 months postoperatively. Although the patients undergoing AVR were younger and had less complex cardiac impairment, their right ventricular function deteriorated significantly in the early post-operative phase (TAPSE -10.52mm, RVPSV -4.23cm / s, FAC -10.22%, p <0.001) and the...
The role of thromboelastometry in monitoring the response to antiplatelet therapy: our experiences and review of literature
Samos M, Simonova R, Bolek T, Skornova I, Stanciakova L, Stasko J, Mokan M
Cardiology Letters 2022, 31(4):221-228
Aim: Insufficient response to antiplatelet therapy, so called high on-treatment platelet reactivity (HTPR), has been repeatedly associated with increased risk of adverse ischemic events. Rotational thromboelastometry (ROTEM®) is a novel viscoelastic hemostatic assay which could, in theory, overcome some limitations of currently available platelet function testing assays. The aim of the article is to report our experiences with the use of ROTEM® for assessment of HTPR in patients with acute myocardial infarction (MI) and review the current experience with the use of the assay for platelet function testing and for monitoring of the response to...
Review
Perspectives of mitochondrial cardiology
Gvozdjáková A
Cardiology Letters 2022, 31(4):229-235
Mitochondria are small dynamic subcellular particles that, under physiological conditions, provide the required amount of energy for continuous heart muscle function. Dysfunction of mitochondria of the myocardium belongs among the basic molecular mechanisms of the origin and development of cardiovascular diseases. The application of the latest diagnostic procedures and targeted therapy of mitochondrial diseases is a perspective of mitochondrial cardiology. New, noninvasive, diagnostic markers of mitochondrial bioenergetics include high-resolution respirometric analysis of platelet mitochondria or peripheral blood mononuclear cells (PBMCs). Taking into...
Right heart catheterization - methodology, indications, focus on patients in cardiogenic shock
Kalvodová Z
Cardiology Letters 2022, 31(4):236-248
Right heart catheterization is a hemodynamic examination used since the 1970s. Over the 50 years of its existence it has undergone dynamic development. While it has an irreplaceable and specifically defined role in some indications, its use in patients in cardiogenic shock is less unambiguous. Cardiogenic shock is a serious clinical condition burdened with high mortality despite advances in treatment methods. Timely and accurate diagnosis of shock is the basis of its successful treatment. Data from mainly observational studies suggest that treatment based on complete hemodynamic monitoring using a pulmonary artery catheter leads to a reduction in mortality....
Case report
MINOCA: myocardial infarction without coronary artery obstruction - case report and review of literature
Snopek P, Hasilla J, Patrovič L, Juskanič D, Benko J, Samoš M
Cardiology Letters 2022, 31(4):249-254
The definition of myocardial infarction without coronary artery obstruction (MINOCA) is found in the fourth Universal Definition of Myocardial Infarction. The main point of diagnosis is the negative finding of hemodynamically significant stenosis of coronary arteries. From an etiological point of view, the cause of MINOCA can be coronary, myocardial, or non-cardiac. In terms of functional status, as well as mortality, there is no significant difference between MINOCA and myocardial infarction with coronary artery obstruction. We present a review and a case report describing this topic. The patient was admitted for acute coronary syndrome without persistent...