Cardiology Letters, 2021 (vol. 30), issue 1

Komentár k Odporúčaniam ESC pre manažment pacientov so supraventrikulárnymi tachykardiami z roku 2019

Hlivák P, Hatala R

Cardiology Letters 2021, 30(1):5-9  

Prečo dnes na Slovensku excesívne zomierame pre SARS-CoV-2?

Dúbrava M

Cardiology Letters 2021, 30(1):10-13  

Incidence and severity of erectile dysfunction in patients with hypertension

Labudová M, Beňačka J, Zambojová I

Cardiology Letters 2021, 30(1):37-41  

Objective: To monitor possible changes in the incidence and severity of erectile dysfunction (ED) in hypertensive patients in relation to the targeted intervention by a nurse aimed at adopting the correct principles of lifestyle of a hypertensive patient. Methods: In a group of randomly enrolled 200 patients aged 40 to 70 years, the questionnaire gathered data on the incidence and severity of erectile dysfunction as well as on the adherence to the correct principles of lifestyle and quality of life. Data collection was repeated after a year, while in half of the patients a nurse performed a periodic targeted intervention during the year. Results: In...

Interaction of perivascular adipose tissue and H2S in mesenteric artery in experiment

Golas S, Berényiová A, Majzúnová M, Čačányiová S

Cardiology Letters 2021, 30(1):42-51  

Introduction: Perivascular adipose tissue (PVAT) and hydrogen sulphide (H2S) play important role in modulation of vasoactive responses and may interfere with the etiopathogenesis of essential hypertension. The aim of this study was to evaluate the mutual relationship between PVAT and H2S (endogenously produced and exogenous) in vasoactive responses of isolated mesenteric arteries in adult normotensive (Wistar) and spontaneously hypertensive rats (SHR). Material and methods: Adult male Wistar and spontaneous hypertensive rats (SHRs) were used. Changes in the isometric tension of MA with or without PVAT were measured after transmural nerve stimulation...

Venous thromboembolism in pregnancy: what the latest real-world data say

Remková A

Cardiology Letters 2021, 30(1):14-18  

Venous thromboembolism (VTE) is a leading cause of maternal mortality. Diagnosis of VTE during pregnancy and post-partum period is challenging. Real-world data on clinical presentation and management of VTE in these women have been limited so far. A recent prospective analysis in a cohort of 596 pregnant and 523 post-partum women with objectively confirmed VTE represents the largest study to date in this population. Pregnant and post-partum women were enrolled from a prospective clinical RIETE registry of real-world patients with VTE. This investigation extended our knowledge by showing that pregnant and postpartum women with VTE had a low incidence...

Arterial hypertension and cognitive functions in seniors

Dúbrava M, Jánošiová J

Cardiology Letters 2021, 30(1):19-22  

Dementia and arterial hypertension (AH) belong to the key non-infectious epidemics in the 21st century, both with a high potential to significantly deteriorate the quality of life as well as shorten the life expectation. Nowadays, we can consider it proven, that middle-aged AH predicts cognitive impairment and dementia (Alzheimer´s and vascular type) in advanced age. AH is considered an equally strong risk factor for cognitive impairment as for chronic kidney disease or atrial fibrillation. So far, the treatment options for dementia are still relatively limited. Therefore, we need to pay more attention to any intervention, that can reduce or at least...

Dual inhibition of neprilysin and angiotensin II type 1 receptor in light of clinical studies

Baka T, Stanko P, Hrenák J, Dukát A, Šimko F

Cardiology Letters 2021, 30(1):23-30  

Despite advances in heart failure (HF) pharmacotherapy over the last three decades, the residual mortality with HF remains high. The antipode to the drug-induced inhibition of vasoconstrictive and proliferative substances could be an increase of vasodilative and antiproliferative humoral substances, including the natriuretic peptides (NPs). NPs are secreted by the distended myocardium and stimulate diuresis and vasodilation, exert antiproliferative effects, and inhibit both the sympathetic and renin-angiotensin systems (RAS). The proteolytic enzyme neprilysin cleaves NPs and thus limits their effects. However, this non-specific protease degrades a...

The use of deformation parameters in assessment of left ventricle subclinical dysfunction

Beňačka O, Gonçalvesová E

Cardiology Letters 2021, 30(1):31-36  

Normal ejection fraction does not truly mean normal systolic function of the myocardium. The ejection mechanism is a complex motion consisting of many shears and rotation. The deformation in longitudinal direction is the most vulnerable part of this complex move. The initial impairment of longitudinal strain is not truly visible by simple, eyeballing, in the echocardiographic examination. The speckle tracking method is an appropriate method to detect such small impairments. In the last 15 years this method has became standard, the reference values have been set up and finally it has found clinical applications. It seems to be useful in cases in which...

Transcatheter mitral valve replacement with Tendyne valve: The first two cases in Slovakia

Hulman M, Bena M, Gasparovic I, Ftacnikova A, Artemiou P

Cardiology Letters 2021, 30(1):53-56  

Eosinophil - "a good servant but a bad master"

Šimovičová V, Danková M, Luknár M, Lesný P, Lauko V, Talarčík P, Gonçalvesová E

Cardiology Letters 2021, 30(1):57-61  

Eosinophilic myocarditis (EM) is a rare form of myocarditis with a very heterogeneous etiology. It is characterized by the presence of eosinophilic infiltrate in the myocardium. The course can vary from an asymptomatic clinical picture to life-threatening conditions. We describe a case of a 29-year-old patient with a history of bronchial asthma hospitalized for chestpain and manifesting heart failure. A moderate decrease of ejection fraction of the undilated left ventricle chamber was found. High levels of troponin, NTproBNP and eosinophilia were present in the laboratory findings. By endomyocardial biopsy we confirmed the presence of an eosinophilic...

10. (virtuálne) stretnutie zástupcov centier pre pľúcnu artériovú hypertenziu

Chudy M, Goncalvesova E

Cardiology Letters 2021, 30(1):62-67  

Deskripcia praxe ambulantných kardiológov

Beňačka J, Beňačka O

Cardiology Letters 2021, 30(1):68-75