Cardiology Letters, 2017 (vol. 26), issue 3
Original article
Management of patients with Acute Coronary Syndromes in Slovakia in 2015. Current analysis of the SLOVAKS registry.
Studenčan M, Hricák V, Kovář F, Kurray P, Kamenský G, Šimková I, Hatala R
Cardiology Letters 2017, 26(3):125-137 
In 2015 a periodical snapshot of the SLOVAKS registry, related to the management of patients with acute coronary syndromes, was made. Results: 1704 patients with ACS were analysed. STEMI represented 32.5% of cases, UA 29.5%, NSTEMI 36.4% and 1.6% had LBBB on ECG. In category of ACS without ST elevation 75.8% belonged to the middle risk or high risk group, according to the TIMI risk score. Only 64.6% of patients in this category underwent invasive management. In STEMI patients 73% of them underwent primary reperfusion treatment (pPCI 70.7%, fibrinolysis 2.34%). The median total ischaemic time was 230,5 minutes. 36.6% of all pPCIs were performed outside...
The efficacy of non-pharmacological treatment of obesity in a spa
Belovičová M, Matula P
Cardiology Letters 2017, 26(3):138-144
Aim of the study: To evaluate the effectiveness of non-pharmacological treatment of obesity in patients who underwent a two-week reduction weight-stay in Bardejov Spa, a. s. in the years 2012-2016. We intended to ascertain whether the non-pharmacological treatment of obesity would statistically significantly affect values of total cholesterol (CHOL), triglycerides (TG), HDL cholesterol (high density lipoprotein), LDLcholesterol (low density lipoprotein), uric acid (KM) and glycemia. Methodology: Bardejov Spa a.s. has developed a complex specialized two-week spa stay aimed at weight reduction, which was put into practice in May 2012. During this stay...
Review
Mitochondrial cardiology
Gvozdjáková A, Kucharská J, Cornélissen G, Singh RB, Šimko F
Cardiology Letters 2017, 26(3):145-163
Mitochondrial Cardiology is part of Mitochondrial Medicine, which provides a comprehensive view of mitochondrial disease in terms of clinical, metabolic, genetic and pathological information relevant to the diagnosis and treatment of mitochondrial diseases. Mitochondrial cardiology highlights the irreplaceable importance of mitochondria in the heart muscle in terms of generating the required amount of energy in the form of ATP through oxidative phosphorylation and reducing oxidative stress. Mitochondrial respiratory chain complexes - I, III and IV form stable supercomplexes that contribute to the elucidation of the causes of mitochondrial diseases....
Case report
What is a thrombus wedged in the patent foramen ovale capable of?
Böhm A, Hricák V, Kozlovský M, Sumbal J, Majerčík M, Tomašovič B, Baranová E, Péč J
Cardiology Letters 2017, 26(3):164-169
Case description: A 49-year-old male was transferred to CCU with recent massive, but hemodynamically stable, pulmonary embolism (PE) followed by symptomatic embolic stroke 3 days before the CCU admission. TEE echocardiography showed thrombus in foramen ovale (PFO), CCD Ultrasonography showed thrombi in the right popliteal vein. Emergent surgical thrombectomy and PFO closure were successfully performed. However the postoperative period was complicated by hemodynamic instability requiring ECMOECLS, recurrent massive PE, infection with disseminated intravascular coagulopathy and diffuse bleeding on continual heparin treatment. After multiple surgical...