Cardiology Letters 2020, 29(5):320-324
Ascending aortic aneurysm and treatment with the PEARS method
- 1 Klinika kardiochirurgie, Národný ústav srdcových a cievnych chorôb, a. s., Bratislava
- 2 Lekárská fakulty, Univerzita Komenského v Bratislave
Dilatation of the aortic root or ascending aorta is a commom condition, especially in patients with genetic disorders like Marfan syndrome, Loyes-Dietz syndrome, Ehlers-Danlos syndome and bicuspid aortic valve disease. Prophylactic replacement of the aortic root/ascending aorta aims to mitigate the risk of dissection or rupture. Current established surgical techniques are there placement of the aortic root/ ascending aorta or the valve sparing root replacement. Personalized external aortic root support (PEARS) is an emerging technology that was developed as an alternative surgical method to aortic root replacement in patients with Marfan syndrome. In this review article we describe the indications, the surgical technique, the advantages and the worldwide experience of the PEARS method.
Keywords: ascending aorta aneurysm; Marfan syndrome; PEARS
Published: May 1, 2020 Show citation
References
- Braveman AC, Thompson RW, Sanchez LA. Diseases of the aorta. In: Bonow RO, Mann DL, Zipes DP, et al. Braunwald´s Heart Disease 9th ed. Philadelphia: Elsevier Saunders; 2012:13091337.
- Erbel R, Aboyans V, Boileau C, et al. 2014 ESC guidelines on the diagnosis and treatment of aortic diseases. Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. Eur Heart J 2014;35:2873-2926.
- Vriz O, Driussi C, Bettio M, et al. Aortic root dimensions and stiffness in healthy subjects. Am J Cardiol 2013;112:1224-1229.
Go to original source... - Prakash P, Patni R, Asghar NM, et al. Ascending aortic aneurysms: pathophysiology and indications for surgery. Cardiol Pract 2011;10:7.
- Bloodwell RD, Hallman GL, Cooley DA. Aneurysm of the ascending aorta with aortic valvular insufficiency: surgical management. Arch Surg 1966;92:588-599.
Go to original source... - Saliba E, Sia YT. The ascending aortic aneurysm: When to intervene. IJC Heart and Vasculature 2015;6:91-100.
Go to original source... - Criado FJ. Aortic dissection: a 250-year perspective. Tex Heart Inst J 2011:38:694-700.
- Barman M. Acute aortic dissection. CardioLPract 2014;12:25.
- Coady MA, Rizzo JA, Hammond L, et al. What is the appropriate size criterion for resection of thoracic aortic aneurysms? J Thorac Cardiovasc Surg 1997;113:476-491.
Go to original source... - Shrestha ML, Beckmann E, Alhadi FA, et al. Elective David I procedure has excellent long-term results: 20 year single center experience. Ann Thorac Surg 2018;105:731-738.
Go to original source... - Bechtel JFM, Misfeld M, Sievers HH. Technique for aortic root replacement: David, Yacoub and Bentall procedures. Zeitschrift fur herz-thorax und gefasschirurgie 2010;24:14-21.
Go to original source... - Silva VF, Real DSS, Branco JNR, et al. Bentall and De Bono surgery for correction of valve and ascending aortic disease: long-term results. Rev Bras Circ Cardiovasc 2008;23:256-261.
Go to original source... - https://exstent.com/the-background/
- Treasure T, Takkenberg JJM, Golesworthy T, et al. Personalised external aortic root support (PEARS) in Marfan syndrome: analysis of 1-9 year outcome by intention-to-treat in a cohort of the first 30 consecutive patients to receive a novel tissue and valve-conserving procedure, compared with the published results of aortic root replacement. Heart 2014;100:969-975.
Go to original source... - Nemec P, Pepper J, Fila P. Personalized external aortic root support. Interact Cardiovasc Thorac Surg 2020;31:342-345.
Go to original source... - Vanderveken E, Vastmans J, Verbelen T, et al. Reinforcing the pulmonary artery autograft in the aortic position with a textile mesh: a histological evaluation. Interact Cardiovasc Thorac Surg 2018;27:566-573.
Go to original source... - Pepper J, Izgi C, Takkenberg JJM, et al. Personalized external aortic roo tsupport (PEARS) to stabilise an aortic root aneurysm. Br J Cardiol 2020;27:93-96.
- Izgi C, Newsome S, Alpedurata F, et al. External aortic roots upport to prevent aortic dilatation in patients with Marfan syndrome. J Am Coll Cardiol 2018;72:1095-1105.
Go to original source... - Lavall D, Schafers HJ, Bom M, et al. Aneurysms of the ascending aorta. Dtsch Arztebl Int 2012;109:227-233.
Go to original source...

