Cardiology Letters 2014, 23(5):353-358
Myocardial neovascularization in the Janus view
- 1 Imunologický ústav Lekárské fakulty Univerzita Komenského v Bratislave
- 2 Oddelenie klinickej patofyziológie Lekárská fakulta Univerzita Komenského v Bratislave, Slovenská republika
The cardiovascular system is developed in order to ensure an optimal supply of oxygen and nutrients to the cells. Neovascularization is the process of forming new blood vessels. Angiogenesis is a complex process of construction of vessels. Angiogenesis also takes place in the myocardium. This review illustrates the formation of new blood vessels in the myocardium at the cellular and molecular level. The authors emphasize the possible impact of treatment on this process.
Keywords: neovascularisation; myocardium; angiogenesis; hypoxia; HIF-1; atherosclerosis
Published: May 1, 2014 Show citation
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