Oficiálny časopis Slovenskej kardiologickej spoločnosti,
Slovenskej hypertenziologickej spoločnosti a Slovenskej asociácie srdcových arytmií

Cardiology Letters 2026, 35(2):83-89

Right ventricular free wall longitudinal strain in heart failure with preserved and mild reduced ejection fraction. Application and prognostic implications

Daniel Grados-Saso1, Juan Manuel Salvador-Casabón1, Anyuli García-Gutiérrez2, Ana María Martínez-Royo1, Juan Ignacio Pérez-Calvo2, Isaac Lacambra-Blasco1
1 Department of Cardiology Hospital Clínico Universitario de Zaragoza, Aragón
2 Department of Internal Medicine Hospital Clínico Universitario de Zaragoza, Aragón, Spain

Aims: Right ventricle (RV) plays an important role in heart failure with preserved and mild reduced ejection fraction. Quantification of right ventricular functional parameters by echocardiography is challenging. In this context an advanced quantification parameter such as right ventricular strain (a measure of myocardial deformation) represents a tool that can provide useful information in the assessment of RV function, with potential prognostic implications.

Methods: In a cohort of 71 prospectively included patients admitted for an episode of heart failure with preserved and mild reduced ejection fraction (LVEF >40%) right ventricular function was evaluated through right ventricular free wall longitudinal strain. Relationship with variables such as hospital readmission and cardiovascular mortality was studied.

Results: Worse right ventricular free wall longitudinal strain was associated to higher probability of cardiovascular mortality at six months. In multivariate analysis RV free wall strain remained a predictor of cardiovascular mortality at 6 months.

Conclusion: In patients with heart failure, impairment of right ventricular free wall strain is related to worse clinical outcome (increased cardiovascular mortality) regardless of other right ventricular functional parameters. Therefore, representing a non-invasive prognostic indicator in these patients, and could be useful in stratifying the risk of adverse events.

Kľúčové slová: Heart failure; HFmrEF; HFpEF; Right ventricular free wall strain

Uverejnené: February 1, 2026  Zobraziť citáciu

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Grados-Saso D, Salvador-Casabón JM, García-Gutiérrez A, Martínez-Royo AM, Pérez-Calvo JI, Lacambra-Blasco I. Right ventricular free wall longitudinal strain in heart failure with preserved and mild reduced ejection fraction. Application and prognostic implications. Cardiology Letters. 2026;35(2):83-89.
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