Oficiálny časopis Slovenskej kardiologickej spoločnosti,
Slovenskej hypertenziologickej spoločnosti a Slovenskej asociácie srdcových arytmií

Cardiology Letters 2025, 34(1):18-28

Súčasné postavenie liekových balónov v intervenčnej kardiológii

Tibor Porubän
I. Kardiologická klinika LF UPJŠ a VÚSCH, a. s., Košice, Slovenská republika

Počet prípadov koronárnej choroby srdca v priebehu uplynulých rokov neustále narastá, a tým stúpa aj význam perkutánnej koronárnej intervencie ako dôležitého terapeutického postupu. Neustály pokrok v medicínskych technológiách neobchádza ani intervenčnú kardiológiu. Hoci čoraz populárnejšie liekové balóny (drug-coated balloons, DCB) nachádzajú uplatnenie v rôznych situáciách a dáta o ich účinnosti a bezpečnosti neustále pribúdajú, odporúčania kardiologických spoločností ich až na malé výnimky dlhodobo prehliadajú. Cieľom tohto článku je preto poskytnúť prehľad aktuálnych poznatkov v tejto oblasti s dôrazom na uplatnenie DCB v rámci revaskularizačných procedúr.

Kľúčové slová: koronárna stenóza; liekové balóny; liekové stenty

Uverejnené: January 1, 2025  Zobraziť citáciu

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Porubän T. Súčasné postavenie liekových balónov v intervenčnej kardiológii. Cardiology Letters. 2025;34(1):18-28.
Share...
Stiahnuť citáciu
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Zobraziť celý článok

    Referencie

    1. Lawton JS, Tamis-Holland JE, Bangalore S, Bates ER, Beckie TM, Bischoff JM, et al. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2022;145:e4-e17. Prejsť k pôvodnému zdroju...
    2. Venkitachalam L, Kip KE, Selzer F, Wilensky RL, Slater J, Mulukutla SR, et al. Twenty-year evolution of percutaneous coronary intervention and its impact on clinical outcomes: a report from the National Heart, Lung, and Blood Institute-sponsored, multicenter 1985-1986 PTCA and 1997-2006 Dynamic Registries. Circ Cardiovasc Interv. 2009;2:6-13. Prejsť k pôvodnému zdroju...
    3. Stefanini GG, Byrne RA, Windecker S, Kastrati A. State of the art: coronary artery stents - past, present and future. EuroIntervention. 2017;13:706-716. Prejsť k pôvodnému zdroju...
    4. Byrne RA, Joner M, Alfonso F, Kastrati A. Drug-coated balloon therapy in coronary and peripheral artery disease. Nat Rev Cardiol. 2014;11:13-23. Prejsť k pôvodnému zdroju...
    5. Jeger RV, Eccleshall S, Wan Ahmad WA, Ge J, Poerner TC, Shin ES, et al. Drug-Coated Balloons for Coronary Artery Disease: Third Report of the International DCB Consensus Group. JACC Cardiovasc Interv. 2020;13:1391-1402. Prejsť k pôvodnému zdroju...
    6. Byrne RA, Joner M, Kastrati A. Stent thrombosis and restenosis: what have we learned and where are we going? The Andreas Grüntzig Lecture ESC 2014. Eur Heart J. 2015;36:3320-3331. Prejsť k pôvodnému zdroju...
    7. Scheller B, Hehrlein C, Bocksch W, Rutsch W, Haghi D, Dietz U, et al. Treatment of coronary in-stent restenosis with a paclitaxel-coated balloon catheter. N Engl J Med. 2006;355:2113-2124. Prejsť k pôvodnému zdroju...
    8. Scheller B, Hehrlein C, Bocksch W, Rutsch W, Haghi D, Dietz U, et al. Two year follow-up after treatment of coronary in-stent restenosis with a paclitaxel-coated balloon catheter. Clin Res Cardiol. 2008;97:773-781. Prejsť k pôvodnému zdroju...
    9. Byrne RA, Neumann FJ, Mehilli J, Pinieck S, Wolff B, Tiroch K, et al. Paclitaxel-eluting balloons, paclitaxel-eluting stents, and balloon angioplasty in patients with restenosis after implantation of a drug-eluting stent (ISAR-DESIRE 3): a randomised, open-label trial. Lancet. 2013;381:461-467. Prejsť k pôvodnému zdroju...
    10. Rittger H, Waliszewski M, Brachmann J, Hohenforst-Schmidt W, Ohlow M, Brugger A, et al. Long-Term Outcomes After Treatment With a Paclitaxel-Coated Balloon Versus Balloon Angioplasty: Insights From the PEPCAD-DES Study (Treatment of Drug-eluting Stent [DES] In-Stent Restenosis With SeQuent Please Paclitaxel-Coated Percutaneous Transluminal Coronary Angioplasty [PTCA] Catheter). JACC Cardiovasc Interv. 2015;8:1695-1700. Prejsť k pôvodnému zdroju...
    11. Xu B, Gao R, Wang J, Yang Y, Chen S, Liu B, et al. A prospective, multicenter, randomized trial of paclitaxel-coated balloon versus paclitaxel-eluting stent for the treatment of drug-eluting stent in-stent restenosis: results from the PEPCAD China ISR trial. JACC Cardiovasc Interv. 2014;7:204-211. Prejsť k pôvodnému zdroju...
    12. Chin K. In-stent restenosis: the gold standard has changed. EuroIntervention. 2011;7(Suppl K):K43-K46. Prejsť k pôvodnému zdroju...
    13. Siontis GC, Stefanini GG, Mavridis D, Siontis KC, Alfonso F, PérezVizcayno M, et al. Percutaneous coronary interventional strategies for treatment of in-stent restenosis: a network meta-analysis. Lancet. 2015;386:655-664. Prejsť k pôvodnému zdroju...
    14. Giacoppo D, Alfonso F, Xu B, Claessen BEMP, Adriaenssens T, Jensen C, et al. Drug-Coated Balloon Angioplasty Versus Drug-Eluting Stent Implantation in Patients With Coronary Stent Restenosis. J Am Coll Cardiol. 2020;75:2664-2678. Prejsť k pôvodnému zdroju...
    15. Vrints C, Andreotti F, Koskinas KC, Rossello X, Adamo M, Ainslie J, et al. 2024 ESC Guidelines for the management of chronic coronary syndromes. Eur Heart J. 2024;45:3415-3537. Prejsť k pôvodnému zdroju...
    16. Alfonso F, Coughlan JJ, Giacoppo D, Kastrati A, Byrne RA. Management of in-stent restenosis. EuroIntervention. 2022;18:e103-e123. Prejsť k pôvodnému zdroju...
    17. Scheller B, Rissanen TT, Farah A, Ohlow MA, Mangner N, Wöhrle J, et al. Drug-Coated Balloon for Small Coronary Artery Disease in Patients With and Without High-Bleeding Risk in the BASKET-SMALL 2 Trial. Circ Cardiovasc Interv. 2022;15:e011569. Prejsť k pôvodnému zdroju...
    18. Lazar FL, Onea HL, Olinic DM, Cortese B. A 2024 scientific update on the clinical performance of drug-coated balloons. AsiaIntervention. 2024;10:15-25. Prejsť k pôvodnému zdroju...
    19. Wybraniec MT, Bańka P, Bochenek T, Roleder T, Mizia-Stec K. Small vessel coronary artery disease: How small can we go with myocardial revascularization? Cardiol J. 2021;28:767-778. Prejsť k pôvodnému zdroju...
    20. Unverdorben M, Kleber FX, Heuer H, Figulla HR, Vallbracht C, Leschke M, et al. Treatment of small coronary arteries with a paclitaxel-coated balloon catheter. Clin Res Cardiol. 2010;99:165-174. Prejsť k pôvodnému zdroju...
    21. Jeger RV, Farah A, Ohlow MA, Shroff A, Wong Y, Ho MY, et al. Drug-coated balloons for small coronary artery disease (BASKET-SMALL 2): an open-label randomised non-inferiority trial. Lancet. 2018;392:849-856. Prejsť k pôvodnému zdroju...
    22. Latib A, Colombo A, Castriota F, De Marco F, Meliga E, De Carlo M, et al. A randomized multicenter study comparing a paclitaxel drug-eluting balloon with a paclitaxel-eluting stent in small coronary vessels: the BELLO (Balloon Elution and Late Loss Optimization) study. J Am Coll Cardiol. 2012;60:2473-2480. Prejsť k pôvodnému zdroju...
    23. Tian J, Tang YD, Qiao S, Su X, Chen Y, Jin Z, et al. Two-year follow-up of a randomized multicenter study comparing a drug-coated balloon with a drug-eluting stent in native small coronary vessels: The RESTORE Small Vessel Disease China trial. Catheter Cardiovasc Interv. 2020;95(Suppl. 1):587597. Prejsť k pôvodnému zdroju...
    24. Cortese B, Di Palma G, Guimaraes MG, Stefanini GG, Siontis KC, Agostoni P, et al. Drug-Coated Balloon Versus Drug-Eluting Stent for Small Coronary Vessel Disease: PICCOLETO II Randomized Clinical Trial. JACC Cardiovasc Interv. 2020;13:2840-2849. Prejsť k pôvodnému zdroju...
    25. Cortese B. The PICCOLETO study and beyond. EuroIntervention. 2011;7(Suppl K):K53-K56. Prejsť k pôvodnému zdroju...
    26. Yu X, Ji F, Xu F, Liu Z, Zhong W, Lu J, et al. Treatment of large de novo coronary lesions with paclitaxel-coated balloon only: results from a Chinese institute. Clin Res Cardiol. 2019;108:234-243. Prejsť k pôvodnému zdroju...
    27. Shin ES, Ann SH, Balbir Singh G, Lim KH, Kleber FX, Koo BK. Fractional flow reserve-guided paclitaxel-coated balloon treatment for de novo coronary lesions. Catheter Cardiovasc Interv. 2016;88:193-200. Prejsť k pôvodnému zdroju...
    28. Lu W, Zhu Y, Han Z, Sun Y, Zhang S, Zhao Q, et al. Short-term outcomes from drug-coated balloon for coronary de novo lesions in large vessels. J Cardiol. 2019;73:151-155. Prejsť k pôvodnému zdroju...
    29. Uskela S, Kärkkäinen JM, Eränen J, Rissanen T, Knuuti J, Heikkilä M, et al. Percutaneous coronary intervention with drug-coated balloon-only strategy in stable coronary artery disease and in acute coronary syndromes: An all-comers registry study. Catheter Cardiovasc Interv. 2019;93:893-900. Prejsť k pôvodnému zdroju...
    30. Cortese B, Silva Orrego P, Agostoni P, Siontis KC, Stefanini GG, Di Palma G, et al. Effect of Drug-Coated Balloons in Native Coronary Artery Disease Left With a Dissection. JACC Cardiovasc Interv. 2015;8:2003-2009. Prejsť k pôvodnému zdroju...
    31. Kumsars I, Holm NR, Niemelä M, Adlam D, Hildick-Smith D, Rasouli M, et al. Randomised comparison of provisional side branch stenting versus a two-stent strategy for treatment of true coronary bifurcation lesions involving a large side branch: the Nordic-Baltic Bifurcation Study IV. Open Heart. 2020;7:e000947. Prejsť k pôvodnému zdroju...
    32. Mathey DG, Wendig I, Boxberger M, Bonaventura K, Kleber FX, Scheller B. Treatment of bifurcation lesions with a drug-eluting balloon: the PEPCAD V (Paclitaxel Eluting PTCA Balloon in Coronary Artery Disease) trial. EuroIntervention. 2011;7(Suppl K):K61-K65. Prejsť k pôvodnému zdroju...
    33. Kleber FX, Rittger H, Ludwig J, Wolny M, Dietz U, Scheller B. Drug-eluting balloons as stand alone procedure for coronary bifurcational lesions: results of the randomized multicenter PEPCAD-BIF trial. Clin Res Cardiol. 2016;105:613-621. Prejsť k pôvodnému zdroju...
    34. Zheng Y, Li J, Wang L, et al. Effect of Drug-Coated Balloon in Side Branch Protection for de novo Coronary Bifurcation Lesions: A Systematic Review and Meta-Analysis. Front Cardiovasc Med. 2021;8:758560. Prejsť k pôvodnému zdroju...
    35. Ybarra LF, Rinfret S, Brilakis ES, Karmpaliotis D, Azzalini L, Grantham JA, et al. Definitions and Clinical Trial Design Principles for Coronary Artery Chronic Total Occlusion Therapies: CTO-ARC Consensus Recommendations. Circulation. 2021;143:479-500. Prejsť k pôvodnému zdroju...
    36. Werner GS, Martin-Yuste V, Hildick-Smith D, Agostoni P, Collet JP, Siontis GC, et al. A randomized multicentre trial to compare revascularization with optimal medical therapy for the treatment of chronic total coronary occlusions. Eur Heart J. 2018;39:2484-2493. Prejsť k pôvodnému zdroju...
    37. Schumacher SP, Stuijfzand WJ, de Winter RW, Hooijman J, Berent P, Van Gaal WJ, et al. Ischemic Burden Reduction and Long-Term Clinical Outcomes After Chronic Total Occlusion Percutaneous Coronary Intervention. JACC Cardiovasc Interv. 2021;14:1407-1418. Prejsť k pôvodnému zdroju...
    38. Neumann FJ, Sousa-Uva M, Ahlsson A, Alfonso F, Banning AP, Benedetto U, et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J. 2019;40:87-165. Prejsť k pôvodnému zdroju...
    39. Yang SS, Tang L, Ge GG, Liu Y, Guo J, Xu J, et al. Efficacy of drugeluting stent for chronic total coronary occlusions at different follow-up duration: a systematic review and meta-analysis. Eur Rev Med Pharmacol Sci. 2015;19:1101-1116.
    40. Köln PJ, Scheller B, Liew HB, Wüstner J, Demir I, Hoebel M, et al. Treatment of chronic total occlusions in native coronary arteries by drug-coated balloons without stenting - A feasibility and safety study. Catheter Cardiovasc Interv. 2017;90:936-943.
    41. Jun EJ, Shin ES, Teoh EV, Fajardo M, Kim HS, Egan A, et al. Acute and long-term outcomes of drug-coated balloon treatment of coronary bifurcation lesions. Circ Cardiovasc Interv. 2016;9:e004079.
    42. Costopoulos C, Latib A, Naganuma T, Kim YH, Waalewijn R, Farah A, et al. One-year outcomes of paclitaxel-coated balloon versus drug-eluting stent for in-stent restenosis: results from the PEPCAD-BIF study. J Am Coll Cardiol. 2018;71:29-39.
    43. Byrne RA, Rossello X, Coughlan JJ, Wittenberg R, Kienlen S, Tilsed P, et al. Coronary revascularization in stable coronary artery disease: a randomized controlled trial. Lancet. 2021;397:11611172.
    44. Vos NS, Dirksen MT, Vink MA, van Nooijen FC, Amoroso G, Herrman JPR, et al. Safety and feasibility of a Paclitaxel-eluting balloon angioplasty in Primary Percutaneous coronary intervention in Amsterdam (PAPPA): one-year clinical outcome of a pilot study. EuroIntervention. 2014;10:584-590. Prejsť k pôvodnému zdroju...
    45. Belkacemi A, Agostoni P, Nathoe HM, Windecker S, Mattheeuw S, Hermans F, et al. Comparative effectiveness of paclitaxeleluting stents in patients with coronary artery disease: A meta-analysis. JACC Cardiovasc Interv. 2017;10:1019-1030.
    46. Scheller B, Ohlow MA, Ewen S, Buechner G, Weidinger F, Di Napoli F, et al. Drug-coated balloon angioplasty for coronary artery disease: current status and future perspectives. EuroIntervention. 2018;14:40-49.
    47. Merinopoulos I, Gunawardena T, Corballis N, Bhalraam U, Gilbert T, Maart C, et al. Paclitaxel drug-coated balloon-only angioplasty for de novo coronary artery disease in elective clinical practice. Clin Res Cardiol. 2023;112:1186-1193. Prejsť k pôvodnému zdroju...
    48. Vos NS, Fagel ND, Amoroso G, Langhans L, Veenstra C, Moll F, et al. Bifurcation lesions: treatment strategy using drug-coated balloons. Heart. 2018;104:1314-1319.
    49. Tao L. Stepwise dual antiplatelet therapy de-escalation in patients after drug-coated balloon angioplasty (REC-CAGEFREE II trial). Prezentované na EuroPCR 2024. 15. máj 2024. Paríž, Francúzsko.
    50. Ouriel K, Adelman MA, Rosenfield K, McManus D, Stoica M, Soni H, et al. Revascularization of chronic total occlusion in patients with severe coronary artery disease. J Vasc Interv Radiol. 2021;32:957-963.

    Späť na obsah